An original article on the development of on-demand metabolically enhanced CAR-T cells, with Dr. Junya Yamaguchi as the lead author, has been published in Science Translational Medicine.
Yamaguchi J, Watanabe K, Nakamura A, Lin NY, Maeda S, Sugiyama D, Kato S, Nagata A, Nishinakamura H, Itahashi K, Koyama S, Mizoguchi H, Shiraki Y, Enomoto A, Ohka F, Motomura K, Tsukada Y, Ito M, Maeda Y, Ueda R, Natsume A, Saito R, Nishikawa H. On-demand GLUT3 expression augments CAR T cell metabolic fitness and antitumor efficacy in preclinical models of glioblastoma. Sci Transl Med. 2026 Apr 15;18(845). doi: 10.1126/scitranslmed.adu3532. Epub 2026 Apr 15. PMID: 41984929.
The findings of this study have also been highlighted in a press release on the Nagoya University website.
Neuro-Oncology
Our Neuroendovascular Surgery Group was recently featured in a Me-Tele (Nagoya Television) program highlighting the medical device manufacturer Fine Biomedical.
The segment introduced scenes from our endovascular procedures, showcasing our commitment to advanced, safe, and patient-centered neurovascular care as well as the clinical application of state-of-the-art medical technologies.
Me-Tele (Nagoya Television)
Professor Ryuta Saito attended the American Society of Clinical Oncology (ASCO) Annual Meeting and presented the results of the multicenter, randomized phase III trial “JCOG1703 (MACS study),” which investigated newly diagnosed glioblastoma.
Link: Professor Ryuta Saito
65 Tsurumai-cho, Showa-ku, Nagoya-shi, Japan, Zip-code:466-8560
J3 minute walk from JR Chuo Main Line Tsurumai Station (Nagoya University Hospital Exit side)
Subway (Tsurumai Line) Get off at Tsurumai Station, 8 minutes on foot.
From city bus "Sakae", take Sakae 18 bound for "Myokencho" and get off at "Meidai Byoin"
The Department of Neurosurgery, Nagoya University Graduate School of Medicine, is located on the 10th floor of Clinical Research Building No. 1.
For details, please refer to the University Hospital website "Transportation Access", Hospital Facilities (Facility Layout).
65 Tsurumai-cho, Showa-ku, Nagoya-shi, Japan, Zip-code:466-8560
